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An elevated ACE activity was found in 17(23%)of 75 patients with MS as compared with 2(6%)of 31 healthy controls.Changes in serum ACE activity correlated with changes in total plaque volume on MRI.Serum ACE activity may be an indicator of disease activity in longitudinal analysis.Also, elevated ACE activity in a patient with otherwise typical MS need not raise suspicions of alternative diagnoses. |
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